NAD+7 Science: How PARP Enzymes Repair Your DNA

Every single day, your cells are under attack. From UV rays and pollution to the normal metabolic processes of eating and breathing, your DNA strands suffer thousands of microscopic breaks and lesions daily. If left unrepaired, this damage accumulates, leading to cellular dysfunction and the visible signs of aging.

Fortunately, your body has a built-in SWAT team dedicated specifically to fixing this damage. This team is a family of enzymes called PARPs (Poly-ADP-Ribose Polymerases).

The "Fuel" Problem: Repair Overload

Think of PARP enzymes as power tools. They are incredibly effective at fixing DNA breaks, but they cannot run without power. That power source is NAD+.

In our article on The 3 Core Reasons We Age, we discussed how cellular damage accumulates over time. PARP is the defense against that damage, but it comes at a cost.

• The Activation: When PARP-1 detects a DNA break, it activates immediately.
• The Cost: To perform the repair, PARP consumes vast amounts of NAD+. It "burns" the fuel to fix the structure.
• Repair Overload: As we age and accumulate more damage, our PARP enzymes enter a state of "Repair Overload." They work overtime, draining your NAD+ levels. This leaves less fuel available for other critical functions like energy production (ATP) and Sirtuin activation.

PARP and Your Brain: Fighting Cognitive Decline (ARCD)

The connection between PARP and NAD+ is nowhere more critical than in the brain. Neurons are high-energy cells that rarely replace themselves. They must be repaired, not discarded.

Age-Related Cognitive Decline (ARCD) is often linked to the cumulative damage of nerve cells. When NAD+ levels drop due to Repair Overload, neurons struggle to maintain their genetic integrity. By fueling PARP enzymes with sufficient NAD+, you provide the "micro" support needed to maintain neural resilience and protect the brain's complex communication network.

The NAD+7 Solution: Refueling the Crew

You cannot stop DNA damage completely—it is a part of life. However, you can support your body's ability to repair it by ensuring your PARP enzymes never run out of fuel.

NAD+7 is formulated to break the depletion cycle:

• Replenish with NR: We provide Nicotinamide Riboside, a direct precursor that helps restore NAD+ levels, giving PARP the raw material it needs to work.
• Protect with Liposomes: Our CELLg8® Technology ensures the ingredients survive digestion to reach the cells where PARP enzymes are active.
• Support with Polyphenols: Ingredients like Resveratrol and Quercetin support a healthy inflammatory response, helping to manage the workload on your repair systems.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.